Profhilo Johannesburg: A Doctor-Led Guide | Radiant Secrets
Published: 14 April 2026 | Updated: 8 September 2026 | Reading time: 9 min
What it is, what it costs, what to expect, and whether it is the right starting point for your skin
Written by Dr Steffani Ovadia | Reviewed by Tholofelo Makgeledise
What is Profhilo in Johannesburg, and why are so many women asking about it?
Profhilo is a bio-remodelling skin booster made of pure, stabilised hyaluronic acid that hydrates the skin from within and stimulates your own collagen and elastin, without adding volume or changing the shape of your face. At Radiant Secrets in Illovo, Johannesburg, it is offered as Profhilo Skin Booster at R4,900 per session, with a first course of two sessions four weeks apart. Results are gradual and subtle: skin looks more hydrated within two to three weeks, and firmer and more luminous four to eight weeks after the second session.
If you have been searching for Profhilo Johannesburg, you are probably noticing that your skin looks a little duller, feels drier by lunchtime, and does not bounce back the way it used to. You are not imagining it, and you are not chasing a dramatic change. This doctor-led guide explains what a Profhilo treatment is, who it suits, what honest results look like, and how it fits into a wider plan for hydration and glow, so you can decide with clarity rather than guesswork.
Key Takeaways
Profhilo is a skin booster, not a filler: it improves skin quality, hydration and firmness, and never reshapes your face.
Profhilo cost in Johannesburg at Radiant Secrets is R4,900 per session, two sessions four weeks apart, then maintenance about every six months.
Downtime is minimal: small bumps at ten injection points settle within hours to a day.
It works on the face, neck, decolletage and hands, the areas that show crepey texture first.
A Doctor-Led Aesthetic Consultation confirms whether Profhilo is your right starting point or whether structure needs attention first.
Skin looking tired and dull? A Profhilo treatment may be the gentle answer.
Leave your number and Dr Stef's team in Illovo will call you back to talk through whether Profhilo Skin Booster suits your skin. No pressure, just honest guidance.
Why does skin change after 45, and why does it matter?
From your mid-forties onward, hyaluronic acid levels drop, collagen production slows, and oestrogen shifts during perimenopause soften the natural scaffolding of the face. The result is skin that looks thinner, feels drier and bounces back more slowly, and this is when many women in Sandton, Illovo and Hyde Park notice that good skincare alone is no longer enough.
About 1% – of skin collagen is lost each year from your twenties onward
64 mg – of pure hyaluronic acid in each 2 ml Profhilo syringe, one of the highest concentrations available
10 points – five Bio Aesthetic Points on each side of the face, chosen for safety and even spread
Topical products only reach the surface, so the deeper changes that affect firmness and glow need support at the level where they are actually happening, which is exactly where a Profhilo skin booster does its work.
What does a Profhilo treatment actually do?
Think of mature skin like a sponge that has dried out: thin, creased and dull. A Profhilo treatment rehydrates that sponge from within and then signals the skin to rebuild its own support over the following weeks.
Pure hyaluronic acid with no cross-linking agents, so it works with your tissue rather than sitting in one spot.
Spreads in a smooth, even layer and releases slowly over about 28 days.
Stimulates four types of collagen and elastin, which is what bio-remodelling means in practice.
Improves hydration, firmness, glow and overall skin quality.
Adds no volume and changes nothing about how your face is shaped.
Profhilo vs filler vs other skin boosters: which is which?
The most common worry we hear is, will this make me look done, and the confusion usually comes from treating every hyaluronic acid injectable as the same thing when they do very different jobs.
Treatment | What it does | Best for | At Radiant Secrets |
|---|---|---|---|
Profhilo Skin Booster | Spreads to hydrate and firm a wide area, stimulates collagen and elastin | Dull, dry, crepey skin and early laxity on face, neck, decolletage, hands | R4,900 per session |
Dermal Filler Treatment | Sits in one area to restore volume, lift and definition | Flattened cheeks, chin, jawline, lower-face heaviness | R3,840 per 1 ml |
Profhilo Structura Cheek Lift | Supports the fat pads of the mid-face for a gentle lift | Early mid-face sagging without wanting filler volume | R5,200 per session |
Juvelook Skin Booster | Biostimulator that builds collagen across the full face over months | Fine lines, texture and long-term skin strength | R7,000 per session |
Liquid Facelift | Combines collagen biostimulation with precise volumising | Significant jowling, sagging and volume loss | R10,000 |
Many women benefit from both skin quality work and structural support, layered over time as part of a tailored plan, not on the same day. If deeper facial heaviness or volume loss is the main concern, Profhilo alone will disappoint, and a plan built around lift and structure gives a far more complete result.
What happens at your Profhilo appointment in Illovo?
Knowing what will happen takes most of the nerves away, and every Profhilo appointment at Radiant Secrets is calm, private and unhurried.
Consultation: Dr Stef assesses your skin, facial structure, ageing pattern and goals, and confirms whether Profhilo is the right starting point. Nothing is recommended that is not genuinely needed.
First session: Profhilo is placed with a fine needle at five Bio Aesthetic Points on each side of the face, a technique known as BAP. It takes about 20 to 30 minutes and most patients describe it as quick and very tolerable.
Aftercare: Small raised bumps at the injection points settle within 4 to 24 hours. You can return to your day straight away, with daily SPF as your main job.
Second session, four weeks later: This completes the course and builds on the collagen and elastin stimulation of the first. Hydration and softness usually show within two to three weeks, and full firmness and glow four to eight weeks after this session.
Maintenance: One session about every six months keeps the result topped up, with medical-grade serums at home protecting what Profhilo builds beneath the skin.
You want to look like yourself again. Just rested.
Friends should notice that you look well, not that you have had something done. If you would like a personalised assessment of whether Profhilo belongs in your plan, we would love to welcome you for a Doctor-Led Aesthetic Consultation.
Common Profhilo myths and mistakes, and how to avoid them
Because Profhilo has become so popular, there is a lot of noise around it, and these are the misunderstandings Dr Stef corrects most often in the consultation room.
Mistake | Why It Happens | How to Fix It |
|---|---|---|
Expecting Profhilo to lift or reshape the face | Profhilo and filler are both hyaluronic acid, so they get lumped together online | Choose Profhilo for skin quality; structure is treated separately when it is genuinely needed |
Booking one session and judging it too soon | Results build over weeks and the course is designed as two sessions | Complete both sessions four weeks apart and assess at eight weeks after the second |
Dropping skincare because you have had a treatment | It feels like the injectable should do all the work | Keep medical-grade serums and daily broad-spectrum SPF to protect and extend the result |
Treating only the face | Most marketing shows faces, yet the neck, chest and hands age visibly early | Ask about treating the neck, decolletage or hands where crepey texture shows |
Choosing on price or trend rather than on your face | Social media makes every treatment look right for everyone | Start with a doctor-led consultation that tells you what will help most and what you can skip |
Dr Stef's tip: If you have an event coming up, book your first Profhilo session about ten weeks before it. That gives the full two-session course time to settle so you arrive looking rested, not recently treated.
A realistic example: what Profhilo before and after looks like
Picture a woman in her early fifties from Hyde Park who comes in because her foundation has started settling into fine lines and her neck looks crepey on video calls. She does not want volume and is nervous about looking different. At her consultation, Dr Stef confirms that her structure is still well supported and that skin quality is the real issue, so Profhilo Skin Booster on the face and neck is a sensible starting point.
After two sessions four weeks apart, plus a simple serum and SPF routine at home, her skin looks more hydrated by week three and noticeably firmer and brighter by week eight. Colleagues ask whether she has been on holiday. She returns for a maintenance session about six months later. Every face responds in its own way and no result can be guaranteed, but this is the subtle, natural-looking outcome Profhilo is designed for.
Frequently asked questions about Profhilo in Johannesburg
How much does Profhilo cost in Johannesburg?
At Radiant Secrets, Profhilo Skin Booster is R4,900 per session. A first course is two sessions, four weeks apart, then one maintenance session about every six months.
How long does Profhilo last?
Results typically last around six months after the two-session course. Most women return for a single maintenance session every six to nine months.
Does a Profhilo treatment hurt?
Most patients describe it as quick and very tolerable. Only five small injection points are used on each side of the face, and any tenderness usually settles within a day.
Is Profhilo the same as filler?
No. Profhilo is a skin booster and bio-remodelling treatment that improves hydration and skin quality. Dermal filler adds volume and shape to one area. Profhilo does not reshape the face.
Is there any downtime after Profhilo?
Downtime is minimal. Small raised bumps at the injection points usually settle within 4 to 24 hours, and most patients carry on with their day straight away.
What do Profhilo before and after results look like?
Subtle. Skin looks more hydrated within two to three weeks, and firmness and glow are usually at their best four to eight weeks after the second session. Nobody should be able to tell you have had anything done.
Can Profhilo be used on the neck, hands and decolletage?
Yes. Profhilo is registered for the face, neck, decolletage and hands, all areas that show crepey texture early. Dr Stef will advise which areas suit your skin.
Can I combine Profhilo with other treatments?
Yes, in a planned sequence. Many patients combine Profhilo Skin Booster with anti-wrinkle injections, dermal filler or a doctor-led facial over several months as part of a tailored plan, never all on the same day.
How Radiant Secrets helps you decide
Profhilo is a beautiful option for the right skin, and it is not the right starting point for every face. That judgement call is exactly what a Doctor-Led Aesthetic Consultation in Illovo is for. Dr Stef will walk you through what your skin actually needs, what it does not need, the sensible order of treatment, and how Profhilo Skin Booster might fit into a calm, tailored plan for ageing well. It is a private, unhurried first step, and you will leave with clarity rather than pressure.
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About the writer
Dr Steffani Ovadia
Founder & Medical Doctor
Steffani qualified as a medical doctor through the University of the Witwatersrand, holding a Bachelor of Health Sciences and an MBBCh. She has spent more than seven years in medicine with a deep focus on aesthetics, and has completed eight aesthetic training courses, including advanced courses covering anti-wrinkle treatments, advanced dermal filler, lip enhancement, cannula technique, Profhilo and more. She trains regularly so that your care always reflects current, considered practice, and in 2026 she was invited to speak at AMCSA, the Aesthetic Medicine Congress of South Africa.
What matters most to Steffani is simple: to restore and protect a woman's confidence. She treats every face with patience and restraint, guiding you honestly toward what will genuinely help, and telling you just as openly what you do not need.
Reviewed by
Tholofelo Makgeledise
Skin Expert & Front of House
Tholofelo is often the first voice you will hear, and the reason so many women feel looked after from the moment they arrive. She is a trained skin expert who has completed her pHformula foundation training and the advanced Expert MD course, with focused skills across the A.C., MELA, C.R. and AGE resurfacing ranges for concerns such as breakouts, pigmentation, and mature or changing skin.
Beyond her facials and skin work, Tholofelo looks after the part women remember most: the aftercare. Her thoughtful follow-up messages, gentle education, and genuine attention are what turn a single visit into a lasting relationship.
